Impact of residence time distributions in reacting magnesium packed-beds on Grignard reagent formation – Selectivity of Grignard reagent formation (part 2)

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چکیده

Grignard reagents are used as intermediates in the production of complex molecules, since they can be to form new carbon-carbon bonds, e.g. formation active pharmaceutical ingredients....

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منابع مشابه

Radical isomerization during Grignard reagent formation. A quantitative treatment.

( l ) (a) Walborsky, H.M.; Young, A. E. J. Am. Chem. Soc. 1961,83, 2595. (b) Walborsky, H. M.; Young, A. E. J. Am. Chem. Soc. 1964, 86,3288. (c) Wafborsky, H. M.; Aronoff, M. S. "/. Organomet. Chem. 1973, 5i,,31. (d) Walborsky, H. M.; Banks, R. B. Bul / . Soc. Chim. Belg.1980,89,849. (2) Ruchardt , C. ; Trautwein, H. Chem. Ber. 1962,95, 1197. (3) Patel , D. J. ;Hami l ton, C. L. ;Roberts, J.D. ...

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The photochemical grafting of methyl groups onto an n-type Si(111) substrate was successfully achieved using a Grignard reagent. The preparation involved illuminating a hydrogen-terminated Si(111) that was immersed in a CH3MgBr-THF solution. The success was attributed to the ability of the n-type hydrogenated substrate to produce holes on its surface when illuminated. The rate of grafting methy...

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ژورنال

عنوان ژورنال: Reaction Chemistry and Engineering

سال: 2023

ISSN: ['2058-9883']

DOI: https://doi.org/10.1039/d3re00191a